Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR52 | DR52 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ EFV+ 3TC | 74 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V106M, M230L | F227FL | E6K, K32KR, V35T, T39R, S48T, K122E, K173A, D177G, T200A, Q207E, R211K, P225S, V245Q, E248D, D250E, S251N, A272P, E291ED, V292I, I293V, S322A |
| >DR52| codons 1-333 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIRALTEICREMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPGIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKESPLLWLGYELHPDKWT VQPIQLPDKENWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35ED, M36I, R41K, K45KR, L63P, H69K, I93L |
| >DR52| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |