Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR51 | DR51 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ AZT+ 3TC | 78 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, M184V | K103KN | P225PH | V35T, T39E, S48T, V60I, D121HY, K122E, I135IL, K173A, D177K, E194ED, T200A, R211K, V241I, V245Q, A272P, K275R, E291D, V292I, I293V |
| >DR51| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEELEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPKIVI YQYVDDLYVGSDLDIGQHRAKIEELRQHLLKWGFTTPDKKHQKEHPFLWMGYELHPDKWT IQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82T | L10F | T12S, I15V, L19T, M36L, N37S, K45R, L63P, H69K, L89M, I93L, C95F |
| >DR51| codons 1-99 PQITLWQRPFVSIKVGGQTKEALLDTGADDTVLEELSLPGRWKPRMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPTNIIGRNMLTQLGFTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |