<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR51 DR51 South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 IDV+ AZT+ 3TC 78

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, M184V   K103KN P225PH V35T, T39E, S48T, V60I, D121HY, K122E, I135IL, K173A, D177K, E194ED, T200A, R211K, V241I, V245Q, A272P, K275R, E291D, V292I, I293V  
>DR51| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEELEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPKIVI
YQYVDDLYVGSDLDIGQHRAKIEELRQHLLKWGFTTPDKKHQKEHPFLWMGYELHPDKWT
IQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82T L10F T12S, I15V, L19T, M36L, N37S, K45R, L63P, H69K, L89M, I93L, C95F  
>DR51| codons 1-99
PQITLWQRPFVSIKVGGQTKEALLDTGADDTVLEELSLPGRWKPRMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPTNIIGRNMLTQLGFTLNF

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008