Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR46 | DR46 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV+ D4T+ DDI | 39 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, D67DN | K219KR | V106M, G190A | F227FL | V35T, T39E, S48T, S68SG, K101X, K122E, S162C, K173A, D177E, T200A, Q207E, V245E, E248N, A272P, E291D, I293V, L310Q |
| >DR46| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKRKNGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLXKKKSMTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAQNPEIVI YQYMDDLYVASDLEIGQHRAKIEELREHLLRWGFTTPDRKHQKEPPLLWMGYELHPDKWT VQPIELPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDVVPLTEEAE LELAENREIQKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, N37NS, R41K, L63P, H69K, I93L |
| >DR46| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |