<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR44 DR44 South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ RTV+ DDI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A   L10I, I15V, L19I, K20R, M36I, N37S, H69K, L89M, I93L  
>DR44| codons 1-99
PQITLWQRPIVTIKVGGQIREALLDTGADDTVLEEISLPGRWKPKIIGGIGGFVKVRQYD
QILIEICGKKAIGTVLVGPTPANIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR, L74LV       K11H, V35T, T39N, S48T, V60I, D121Y, K122E, S162C, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, A272P, K277R, T286TA, E291D, V292I, I293V  
>DR44| codons 1-335
PISPIETVPVHLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKITKIGPENPYNTPI
FAIKRKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAKNPELVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008