Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR41 | DR41 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ DDI | NA |
| 2 | AZT+ 3TC+ NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, L210W, T215Y | K219KN | Y181C, M230L | A98G | T39D, E44D, S48T, K122E, D123S, S162C, I167V, K173A, D177DE, T200A, Q207E, L228H, Q242H, V245Q, P247A, K249Q, A272P, K275Q, Q278H, T286A, E291D, V292I, I293V, Q334X |
| >DR41| codons 37-334 ICDELEKDGKITKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPH PGGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGS PAIFQCSMTKVLEPFRAQNPEIVICQYVDDLYVGSDLEIGQHRAKIEELREHLWRWGFYT PDNKHQKEPPFHWLGYELHPDKWTVHPIQLAEQDSWTVNDIQKLVGKLNWASQIYPGIQV KHLCKLLRGAKALTDIVPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGX |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, T12S, I15V, M36I, R41K, Q61E, L63V, H69K, L89M, I93L |
| >DR41| codons 1-99 PQITLWQRPIVSIKVGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD EIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |