Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR37 | DR37 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T+ AZT+ DDI | NA |
| 2 | NFV+ DDI+ ABC | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74IV, M184V | K219KE | V35M, T39D, S48T, V60VI, D123DN, K173A, Q174K, T200A, E203K, Q207E, R211K, V245Q, K249KQ, D250E, A272P, K277R, E291D, V292I, I293V |
| >DR37| codons 1-309 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICDEMEKEGKITKIGPENPYNTPI FAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKNFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDIVI YQYVDDLYVGSDLEIGQHRAKIKELREHLLKWGFTTPDEKHQKEPPFLWMGYELHPDKWT VQPIQLPEQESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREI |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, N88S, L90M | L10F | T12S, I13V, I15V, L19I, K20T, M36I, R41K, L63P, H69K, L89I, I93L |
| >DR37| codons 1-99 PQITLWQRPFVSVKVGGQITEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRSIMTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |