Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR34 | DR34 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ NVP+ AZT | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | T215TI | K103N | Y318YF | V35T, T39K, K46KQ, S48T, V60I, T69TN, K122E, D123G, I135X, K173A, D177EK, I178M, T200A, I202IV, Q207E, R211K, K219X, V245Q, A272P, T286A, E291D, V292I, V317VA |
| >DR34| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGQITKIGPENPYNTPI FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSXNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEMVI YQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGFITPDXKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIIPLTEEAE LELAENREILKEPVHGAFYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, Q18QH, L19I, M36I, R41K, K43KR, L63P, H69K, I93L |
| >DR34| codons 1-99 PQITLWQRPLVSIKVGGHIKEALLDTGADDTVLEEINLPGKWRPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |