<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR33 DR33 South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ D4T 125

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V       V35T, T39E, S48T, V60I, K122E, K173A, Q174K, D177E, I178L, T200A, K201KR, I202V, Q207E, R211K, V241I, V245Q, A272S, E291D, V292I, I293V  
>DR33| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPELVI
YQYMDDLYVGSDLEIGQHRARVEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
IQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K14R, I15V, L19I, K20R, M36I, N37D, L63X, H69K, L89I, I93L  
>DR33| codons 1-99
PQITLWQRPLVTIRVGGQIREALLDTGADDTVLEEIDLPGRWKPKMIGGIGGFIKVRQYD
QIXIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008