Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| DR33 | DR33 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ D4T | 125 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V | V35T, T39E, S48T, V60I, K122E, K173A, Q174K, D177E, I178L, T200A, K201KR, I202V, Q207E, R211K, V241I, V245Q, A272S, E291D, V292I, I293V |
| >DR33| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPELVI YQYMDDLYVGSDLEIGQHRARVEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT IQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, I15V, L19I, K20R, M36I, N37D, L63X, H69K, L89I, I93L |
| >DR33| codons 1-99 PQITLWQRPLVTIRVGGQIREALLDTGADDTVLEEIDLPGRWKPKMIGGIGGFIKVRQYD QIXIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF |
References
| Author | Title | Citation |
| Pillay, V | HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. | ARHR, 2008 |