<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DR15 DR15 South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ AZT NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R K219E     K20R, V35T, T39K, S48T, V60I, V118I, K122E, D123N, A158S, S162G, K173T, Q174A, T200A, E203EK, Q207E, R211K, F214L, V245Q, D250E, S251D, A272P, K277R, Q278E, E291D, V292I, I293V, E297K  
>DR15| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICKEMEKEGKITKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQGSMTKILEPFRTANPDIVI
YQYMDDLYVGSDLEIGQHRAKIKELREHLLKWGLTTPDEKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKEDWTVNDIQKLVGKLNWASQIYPGIKVRELCKLLRGTKALTDIVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, D60E, H69K, T74TS, L89M, I93L  
>DR15| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
QILIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Pillay, V HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. ARHR, 2008