Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14196 | CA35216 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 100 |
| 2 | 3TC+ABC+AZT+NFV | 91 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184V, T215F | K219E | V35I, T39S, V60VI, R83RK, D121Y, K122E, I135T, G196E, F214L, A272P, K275R, R284K, T286A, I293V, P294T |
| >CA35216| codons 1-299 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICSELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRTKIEELRQHLLRWGLFTPDEKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLKGAKALTEVVTLTEEA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | L10I, T12Q, I13V, K14R, E35D, M36I, N37S, R41K, Q61E, I62V, L63P, I64V, C67Y, A71T, I72IT |
| >CA34201| codons 1-99 PQITLWQRPIVQVRIGGQLKEALLDTGADNTVLEDISLPGKWKPKMIGGIGGFIKVRQYD EVPVEIYGHKTTGTVLVGPTPVNIIGRDLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |