Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14538 | CA35183 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+DDI+NVP | 9 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | Y181I | A98S, S162SN, Q174R, T200A, E204D, R211G, E233D, I293V, E297EK, I329IL, R358RK, A376AT, E399ED, A400AT, E404ED, E432ED, V435I, L452LS, S468PT, Q480QE, S519SN, V531VI, A554AS |
| >CA35183| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKRNPDIVI IQYVDDLYVGSDLEIGQHRAKIEDLRQHLLGWGFTTPDKKHQKEPPFLWMGYDLHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGQGQWTYQIYQEPFKNLKTGKYARMKGA HTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWDTWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIIGAETFYVDGAANRETKSGKAGYVTDRGRQKVVTLTDTTNQKTELE AIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKIYLAWVPAHK GIGGNEQVDKLVSSGIRKVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35Q, N37D, R57RK, L63P, A71V, I72V, V77I, I93L |
| >CA34168| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEQMDLPGRWKPKMIGGIGGFIKVKQYD QIPIEICGHKVVGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |