<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA5718 CA35166 U.S. 2002 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 Unknown 52
2 3TC+AZT+IDV 35
3 D4T+DDI+NFV 91
4 3TC+ABC+APV+EFV 18
5 3TC+ABC+APV+NVP 56
6 None 53

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69S_SS, L74V, M184V, T215Y A62V, D67E Y181C, G190S K101H K122E, D177E, T200TA, L228H, A272AS, T286A, I293IV  
>CA35166| codons 1-295
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FVIKKKESSKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLHKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
CQYVDDLYVSSDLEIGQHRAKIEELRQHLLRWGFYTPDKKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTEVVPL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, I47IV, I54IV, V82A, L90M L33F, K43T L10I, L19I, K20KR, E35D, M36I, M46X, L63P, I64V, I66IF, A71V, I93IL  
>CA34151| codons 1-99
PQITLWQRPIVTIKIGGQIREALLDTGADDTIFEDINLPGRWTPKXVGGIGGFVKVRQYD
QIPVEFCGHKVIGTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005