Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14242 | CA35089 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | 3TC+APV+DDI+EFV+RTV+SQV+TDF | 22 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, L210W, T215Y | K219Q | K101KE, K103KN, Y181C, G190A | A98G | V35E, T39A, E40F, V106VI, K122E, D123N, G196E, E203K, Q207E, H208HY, K223E, L228H, A272P |
| >CA35089| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALEEICAFLEKEGKISKIGPENPYNTPV FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPGGLEKNKSITVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVASDLEIEQHRTKIKELREYLWRWGFYTPDQKHQEEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I50IV, I54V, V82A, L90M | L10F, L33F | I13V, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63P, A71V, I85V |
| >CA34079| codons 1-99 PQITLWQRPFVTVKIGGQLREALLDTGADDTVFEDIDLPGKWKPKIIGGVGGFVKVKQYD QVPIEICGHKVIGTVLVGPTPANIVGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |