<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA14611 CA35024 U.S. 2002 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 104
2 3TC+AZT 209
3 3TC+AZT+SQV 147
4 3TC+AZT+RTV+SQV 96

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, M184V, L210W, T215Y K219N     V35VE, T39A, E40F, K43E, V60I, S68G, V118I, K122E, K166R, G196E, T200I, R211K, A272P, I293V E302D
>CA35024| codons 1-302
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALEEICAFLEEEGKISKIGPENPYNTPI
FAIKKKDGTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI
YQYVDDLYVGSDLEIEQHRIKIEELRQHLWKWGFYTPDNKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE
LD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, V82AT, L90M F53FL L10I, K20R, E35D, M36I, N37D, I62IV, L63P, H69HR, A71V, T74S  
>CA34006| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPGRWKPKMIVGIGGLIKVRQYD
QVPIEICGRKVIGSVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005