Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6497 | CA34983 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 52 |
| 2 | 3TC+D4T+IDV | 182 |
| 3 | 3TC+D4T+NFV+NVP | 95 |
| 4 | ABC+D4T+RTV+SQV | 121 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | G190A | K101H | T39A, E44D, V60VI, V118X, I135T, I142V, S162C, A272AP, K277R, Q278H, I293V |
| >CA34983| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKDGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLHKKKSVTVLDVGDAYFSXPL DKDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYMDDLYVASDLEIGQHRTKIEELRQHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRHLCKLLRGTKALTEVVPLTEEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, G48GV, I54IV, V82A, I84IV, L90M | L23LI, F53FL | L10IV, M36I, R41RK, I62V, L63P, A71V, T74TS, I93L |
| >CA33964| codons 1-99 PQITLWQRPIVTIKIGGQLKEAILDTGADDTVLEEINLPGKWKPKLIVGIGGLVKVRQYD QVPIEICGHKVIGSVLVGPTPANVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |