Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14153 | CA34968 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 48 |
| 2 | D4T | 22 |
| 3 | 3TC+AZT | 13 |
| 4 | 3TC+AZT+NVP | 231 |
| 5 | DDC+RTV+SQV | 45 |
| 6 | 3TC+DDI+EFV+TDF | 36 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184MV, L210W, T215Y | A62AV | K103N, V106A | P225PH, F227FL | V35L, T39A, K43E, E44D, R83K, K122E, D123E, S162X, D177E, I178L, G196E, R211K |
| >CA34968| codons 1-275 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICAELEEDGKISKIGPENPYNTPV FVIKKKNSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKNKSATVLDVGDAYFSVPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQXSMTKILEPFRKQNPELVI YQYVDDLYVGSDLEIEQHRTKIEELRQHLWKWGFYTPDKKHQKEHPLLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIK |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L63P |
| >CA33953| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |