Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7916 | CA34892 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T | 57 |
| 2 | 3TC+D4T | 9 |
| 3 | 3TC+AZT+IDV | 65 |
| 4 | 3TC+D4T+NFV | 174 |
| 5 | 3TC+AZT+NVP | 90 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101KE, G190A | A98AG | E6EK, T39A, K103X, T107TS, K122E, D123E, I142V, S162A, D177E, V179I, F214L, V245T, A272P, I293V, E297A |
| >CA34892| codons 1-300 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLEKXKSVSVLDVGDAYFSVPL DEEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPEIII YQYVDDLYVASDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTAEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | L10V, E35D, M36V, L63P, A71V, I93L |
| >CA33877| codons 1-99 PQITLWQRPVVTIKIGGQLKEALLDTGADNTVLEDVNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKVIGTVLVGPTPVNIIGRDLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |