<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
99022008 99022008 South Africa 2011 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV 128

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, M184V K219KR K101E, V106M F227L T27S, V35T, T39DE, V60I, K103R, I135V, E138A, T139I, K173T, Q174K, D177E, V179A, T200A, I202V, Q207E, F214L, V245Q, A272P, K277T, T286A, E291D, V292I, I293V, Q334H, G335D  
>99022008| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALTEICEEMEKEGKISKIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKRKSMTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNAIPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIAI
YQYVDDLYVGSDLEIGQHRAKVEELREHLLRWGLTTPDRKHQKEPPLLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVTQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19V, M36I, R41K, L63P, H69K, L89M, I93L  
>99022008| codons 1-99
PQITLWQRPLVSIKVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Lam, EP Antiretroviral resistance after first-line antiretroviral therapy failure in diverse HIV-1 subtypes in the SECOND-LINE study. ARHR, 2016