Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5632 | CA34882 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
| 2 | AZT+NFV+NVP | 21 |
| 3 | APV+RTV+ABC+EFV | 26 |
| 4 | AZT+3TC+LPV+EFV | 85 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T215Y | V106A, G190A | F227L | L109I, K122E, V179I, I202V, D218E, L228LR, A272P, K277R, Q278H, I293V, E297K |
| >CA34882| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVIDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYMDDLYVASDLEIGQHRTKVEELRQHLLRWGFYTPEKKHQKEPPLRWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRHLCKLLRGTKALTEVVPLTKEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L76V, I84V, L90M | G73S | T12TK, I15V, K20I, R57K, Q61R, I62V, L63P, C67F, H69K, A71V, I72L |
| >CA33867| codons 1-99 PQITLWQRPLVKIKVGGQLIEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFVKVKQYD RVPIEIFGKKVLSTVVVGPTPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |