Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 21032003 | 21032003 | Nigeria | 2010 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NVP | 266 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, D67N, K70R, M184V | V75I, T215TI, K219E | K101EQ, Y181C | A98AG, V108I | K20R, V35T, E36D, T39A, A62T, T69TN, R83K, V90I, I135V, S162A, K173AT, Q174K, N175NY, D177E, T200A, Q207E, V245Q, V276VI, Q278N, T286A, E291D, V292I, I293IV, P294T, S322T, I326V, G335D |
| >21032003| codons 1-335 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTDICAELEKEGKISKIGPENPYNTPV FTIKKKNSNRWRKLIDFRELNKKTQDFWEIQLGIPHPGGLQKKKSVTILDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKYPEIVI CQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFITPDEKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKNLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13A, K14KR, I15V, K20I, M36I, R41K, L63P, H69K, L89M |
| >21032003| codons 1-99 PQITLWQRPLVTARVGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Lam, EP | Antiretroviral resistance after first-line antiretroviral therapy failure in diverse HIV-1 subtypes in the SECOND-LINE study. | ARHR, 2016 |