<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
21032003 21032003 Nigeria 2010 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP 266

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, D67N, K70R, M184V V75I, T215TI, K219E K101EQ, Y181C A98AG, V108I K20R, V35T, E36D, T39A, A62T, T69TN, R83K, V90I, I135V, S162A, K173AT, Q174K, N175NY, D177E, T200A, Q207E, V245Q, V276VI, Q278N, T286A, E291D, V292I, I293IV, P294T, S322T, I326V, G335D  
>21032003| codons 1-335
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTDICAELEKEGKISKIGPENPYNTPV
FTIKKKNSNRWRKLIDFRELNKKTQDFWEIQLGIPHPGGLQKKKSVTILDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKYPEIVI
CQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFITPDEKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKNLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13A, K14KR, I15V, K20I, M36I, R41K, L63P, H69K, L89M  
>21032003| codons 1-99
PQITLWQRPLVTARVGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Lam, EP Antiretroviral resistance after first-line antiretroviral therapy failure in diverse HIV-1 subtypes in the SECOND-LINE study. ARHR, 2016