<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
16012023 16012023 India 2011 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 501

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, K70R, M184V K219KQ K103N   K20R, V35T, E36EA, T39DE, S48T, K49KR, V60I, V90I, D121Y, K122E, I135T, E138G, S162H, K173A, D177E, T200A, E203EK, Q207E, R211RK, V245Q, A272P, K277R, K281KR, E291D, V292I, I293V, E297EA, G335D Y232H
>16012023| codons 1-335
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKITRIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSTNNGTPGIRYQYNVLPQGWKGSPAIFQHSMTKILEPFRAQNPEIVI
YQYVDDLYVGSDLEIGQHRAKIKELREHLLKWGFTTPDQKHQKEPPFLWMGHELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGTKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, L19I, M36I, R41K, Q61E, I62V, L63T, H69K, T74A, L89M, I93L  
>16012023| codons 1-99
PQITLWQRPLVSIKIGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
EVTIEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Lam, EP Antiretroviral resistance after first-line antiretroviral therapy failure in diverse HIV-1 subtypes in the SECOND-LINE study. ARHR, 2016