Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7072 | CA34812 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T | 44 |
| 2 | AZT+DDC+IDV | 74 |
| 3 | 3TC+D4T+RTV+SQV | 74 |
| 4 | 3TC+APV+D4T+EFV | 94 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | L100I, K103N | A98AG | E6EK, K43KQ, E44ED, V118VI, K122E, D123E, I135V, I142IV, S162C, R211K, H221HY, V245E, A272P, K277R, E297K |
| >CA34812| codons 1-301 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEQDGKISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPGGIKKNKSVTVLDVGDAYFSIPL DEEFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKYQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTKEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, V82A, L90M | L33F, F53L | L10LI, T12A, I13V, K14R, N37D, R41RK, L63P, I64V, G68GE, A71V, V77VI |
| >CA33800| codons 1-99 PQITLWQRPIVAVRIGGQLKEALLDTGADDTIFEEMDLPGKWKPKIIGGIGGLIKVRQYD QIPVEICEHKVIGTVLIGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |