<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
GFECB023 GFECB023 South Africa 2013 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 157

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V V75I V106M F227L V35T, T39E, S48T, V60I, V90I, K102Q, L109I, K122E, D123G, I132L, K166R, K173A, T200A, I202V, R211K, H221Y, V245K  
>GFECB023| codons 1-258
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLIDFRELNKRTQDFWEIQLGIPHPAGLKQKKSMTVIDVGDAYFSVPL
DEGFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAQNPDIVI
YQYVDDLYVGSDLEIGQHRAKVEELRQHLLKWGFTTPDKKYQKEPPLLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, K20R, E35D, M36I, R41K, Q61E, L63P, H69K, L89M, I93L  
>GFECB023| codons 1-99
PQITLWQRPLVSIKVGGQTREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
EIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Steegen, K HIV-1 antiretroviral drug resistance patterns in patients failing NNRTI-based treatment: results from a national survey in South Africa. J Antimicrob Chemother, 2016