Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9909 | CA34724 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 13 |
| 2 | 3TC+DDI | 70 |
| 3 | 3TC+D4T+NVP | 242 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215F | Y181C | I31L, T39A, A98S, K122E, I135R, S162C, Q207E, H221Y, V245E, A272P, T286A, I293V |
| >CA34724| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALVEICAEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI CQYVDDLYVGSDLEIGQHRTKIEELREHLLRWGFFTPDKKYQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVPLTEEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19Q, Y59YH, A71T, I72T, V77I, I93L |
| >CA33709| codons 13-99 IKIGGQQKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQHDQILIEICGHKTT GTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |