<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
GFNWB002 GFNWB002 South Africa 2014 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+EFV+TDF NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184I   V106M, Y181C F227L V8I, V35T, T39E, S48T, A62P, S68G, V90I, K122E, D123S, I135V, K173A, Q174R, D177E, T200A, I202V, E203K, Q207E, R211K, H221Y, V245Q, A272P, E291D, V292I, I293V, Q334D, G335D, R356K, M357R, G359T, T377M, K390R, E396D, A400T, E404D, E432D, V435A, G436E, A437V  
>GFNWB002| codons 1-437
PISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FPIKRKDGTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPEIVI
CQYIDDLYVGSDLEIGQHRAKVKELREHLLKWGFTTPDKKYQKEPPLLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKRRTA
HTNDVKQLTEAVQKIAMESIVIWGKTPKFRLPIQKDTWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIAEV

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L19T, M36I, N37D, L38I, H69K, I93L  
>GFNWB002| codons 1-99
PQITLWQRPLVTIKIGGQTKEALLDTGADDTVLEEIDIPGRWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Steegen, K HIV-1 antiretroviral drug resistance patterns in patients failing NNRTI-based treatment: results from a national survey in South Africa. J Antimicrob Chemother, 2016