<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
GFECB037 GFECB037 South Africa 2013 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+EFV+TDF 71

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184V A62V V106M, Y181YC, G190A F227L V35K, T39E, S48T, S68N, K122E, D123S, I135T, S162C, K173A, Q174K, V179I, T200A, I202V, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, I309L, Q334H, G335D, R356K, G359T, T369A, T377L, K390R, A400AT, E404D  
>GFECB037| codons 1-405
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICEEMEKEGKITKIGPENPYNTPV
FVIKRKDNTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAKNPDIII
CQYVDDLYVASDLEIGQHRAKVEELREHLLKWGFTTPDKKHQKEPPLLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENRELLKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLAEAVQKIALESIVIWGKTPKFRLPIQKETWETWWTDY

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, G16E, L19I, Q61E, L63T, I64L, H69K, I72V, V77I, L89M, I93L  
>GFECB037| codons 1-99
PQITLWQRPLVSIKIEGQIKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
EITLEICGKKAVGTVLIGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Steegen, K HIV-1 antiretroviral drug resistance patterns in patients failing NNRTI-based treatment: results from a national survey in South Africa. J Antimicrob Chemother, 2016