<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
GFKZB011 GFKZB011 South Africa 2013 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 165
2 3TC+EFV+TDF 118

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, L74I, Y115F, M184V A62AV K103N, V106M F227L E6K, K20R, T27S, V35T, T39D, S48T, V90VI, K122E, E138EG, S162A, K173T, T200A, Q207K, R211K, V245K, D250E, A272P, K277R, T286A, E291D, V292I, I293V, I326V, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D P4HY, S68SDGN
>GFKZB011| codons 1-410
PISYIKTVPVKLKPGMDGPRVKQWPLSEEKIKALTEICDEMEKEGKITKIGPENPYNTPV
FVIKRKDDTKWRKIVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSMTVLDVGDAFFSVPL
DEDFRKYTAFTIPSINNGTPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTQNPDIVI
YQYVDDLYVGSDLEIGQHRAKIEELRKHLLKWGFTTPDKKHQKEPPLLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWETWWTDYWQATW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, G16E, L19I, E35D, D60E, I62V, H69K, L89M  
>GFKZB011| codons 1-99
PQITLWQRPLVSIKIEGQIKEALLDTGADDTVLEDMNLPGRWKPKMIGGIGGFIKVRQYE
QVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Steegen, K HIV-1 antiretroviral drug resistance patterns in patients failing NNRTI-based treatment: results from a national survey in South Africa. J Antimicrob Chemother, 2016