Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6418 | CA34664 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | 56 |
| 2 | 3TC+D4T+NFV | 82 |
| 3 | D4T+DDI+RTV+SQV | 65 |
| 4 | 3TC+ABC+D4T | 108 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74I, M184V | V75S, T215V, K219Q | K11KR, K64Y, K122E, N175Y, T200A, I202V, Q207E, L228H, A272P, I293V, S322T, Q334E, M357S, T369TA, K385KR, T386TI, K390R, K395R, A400T, K454R, D460N, R461K, S468T, H483Y, Q509L, K530KR | Q547HN |
| >CA34664| codons 1-560 PISPIETVPVRLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIYKKNSTRWRKISDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQYPDIVI YQYVDDLYVGSDLEIGQHRAKVEELREHLLRWGFVTPDQKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYARSRGA HTNDVKQLAEAVQKIATESIVIWGRIPKFRLPIQRETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGRAGYVTNKGRQKVVTLTDTTNQKTELQ AIYLALQDSGLEVNIVTDSQYALGIIQALPDKSESELVSQIIEQLIKKERVYLAWVPAHK GIGGNENVDKLVSAGIRKVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N37S, L63P, V77VI |
| >CA33645| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |