Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA478 | CA34652 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | AZT+DDI | 386 |
| 3 | 3TC+D4T+NVP | 204 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, K70R, Q151M, M184V | V75I, F77L, F116Y, K219KE | K103KN, Y181YC | K101N, V108VI | V35IM, T39A, S68G, E79D, R83K, V90I, A158S, I202V, R211K, D218DE, H221HY, L228LR, V245E, R284K, T286A, E297A |
| >CA34652| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICAEMEKEGKISKIGPENPYNTPV FAIKRKDGTRWRKLIDLRDLNKKTQDFWEIQLGIPHPAGLNKNKSVTILDVGDAYYSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPSIFQSSMTKILEPFRKQNPDIVI CQYVDDLYVGSDLEIGQHRTKVEELRQHLLKWGFTTPEEKYQKEPPFRWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGAKALTEVIPLTAEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13IV, L63P |
| >CA33636| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |