Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6470 | CA34566 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 117 |
| 2 | 3TC+AZT+RTV | 13 |
| 3 | 3TC+AZT+IDV | 198 |
| 4 | ABC+APV+D4T | 102 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L210W, T215Y | K219KR | T39X, E40X, K43E, E44EA, V60I, V75X, V118VI, I142V, Q207E, H208HY, R211RK, Q278H, I293V, P294Q |
| >CA34566| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICXXLEEAGKISKIGPENPYNTPI FAIKKKNSDKWRKLXDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELREYLWKWGFYTPDRKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGTKALTEVVQLTEEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I47IV, I54V, V82A | K43T, L89V | L10I, I13V, K20V, M46X, L63P, A71T |
| >CA33557| codons 1-99 PQITLWQRPIVTVKIGGQLVEALLDTGADDTVLEEMNLPGRWTPKXVGGIGGFVKVRQYD QIPIEICGHKTIGTVLVGPTPANIIGRNVLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |