Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4159 | CA34565 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 13 |
| 2 | 3TC+D4T+NFV | 100 |
| 3 | NVP+RTV+SQV | 61 |
| 4 | D4T+NVP+RTV+SQV | 91 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M | F116Y | K103N, Y181C | V35I, S68G, V90I, D121H, K122E, T139TA, K173Q, Q174R, D177E, I178L, G196E, T200A, R211T, F214L, V245M, E248D, D250A, A272P, E291D, I293V |
| >CA34565| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV FAIKKKDGTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTVLDVGDAYYSVPL HEDFRKYTAFTIPSINNEAPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRQRNPELVI CQYMDDLYVGSDLEIEQHRAKIEELRQHLLTWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPDKASWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDVVPLTEEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, I54V, L90M | L10LF, V11I, F53L, Q58E, N88D | I13V, L19I, K20I, E35N, M36I, N37DE, D60E, Q61E, L63P, A71V, I72T |
| >CA33556| codons 1-99 PQITLWQRPFITVKIGGQIIEALLDTGADNTVLENIDLPGRWKPKMIGGIGGLVKVREYE EIPIEICGHKVTGTVLVGPTPVNIIGRDLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |