Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5271 | CA34532 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 187 |
| 2 | None | 4 |
| 3 | 3TC+AZT | 4 |
| 4 | 3TC+AZT+RTV | 30 |
| 5 | 3TC+AZT+IDV | 113 |
| 6 | None | 12 |
| 7 | 3TC+AZT+IDV | 30 |
| 8 | None | 8 |
| 9 | 3TC+AZT+EFV | 48 |
| 10 | None | 8 |
| 11 | 3TC+ABC+AZT | 63 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, D67~, K70R, L74V, M184V, T215F | T69G, K219Q | A98S, K101X, I135V, D192E, T200TA, R211K, D218DE, L228H, V245T, K277R, L283I, I293V | E29EG |
| >CA34532| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEGKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKK~SGRWRKVVDFRELNKRTQDFWEVQLGIPHPSGLXKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSELEIGQHRAKIEELRQHLLKWGFFTPEQKHQKEPPFHWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLIRGTKALTEVVPLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L63P |
| >CA33518| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |