Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14312 | CA34519 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 169 |
| 2 | 3TC+D4T+NVP | 96 |
| 3 | ABC+NFV+SQV | 159 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, L74LV, V75T, M184V | K219Q | K101KE, G190A | K20R, V35VI, V118I, S162D, V179I, F214L, D237DN, E248DN, A272P | I37L |
| >CA34519| codons 1-301 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIELCTEMEKEGKISKIGPENPYNTPV FAIKKKNSDRWRKVTDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPDIII YQYVDDLYVASDLEIGQHRTKIEELRQHLLRWGLTTPDQKHQKEPPFLWMGYELHPNKWT VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | G73S | L10I, I13IV, E35D, M36I, D60E, Q61D, I62V, L63P, I66IV, H69Q, A71V |
| >CA33503| codons 1-99 PQITLWQRPIVTVKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYE DVPIEVCGQKVISTVLVGPTPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |