Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8395 | CA34441 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 174 |
| 2 | D4T+DDI+RTV+SQV | 50 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184MV | T215I, K219Q | K122P, I142V, Q174QR, D177E, I178IL, R211K, A272P, T286A |
| >CA34441| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DPDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPELVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLKWGFITPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTEEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, I84V, L90M | L33F, F53FL, N88D | I13V, N37S, R41K, D60E, I62V, L63P, A71AT, I72IT, V77I, I93L |
| >CA33426| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADNTVFEEMSLPGKWKPKMIGGIGGLIKVRQYE QVPIEICGHKTTGTVLIGPTPVNVIGRDLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |