Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5159 | CA34426 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 191 |
| 2 | AZT+DDI | 18 |
| 3 | 3TC+AZT+SQV | 22 |
| 4 | 3TC+AZT+IDV | 104 |
| 5 | 3TC+AZT+NFV | 78 |
| 6 | 3TC+AZT+NVP | 167 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V | Y181C | K32KR, K49KR, R83K, I135R, I178L, T200I, F214L, H221Y, V245KR, A272P, R284RK, I293V |
| >CA34426| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIRALVEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSTRWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLVI CQYVDDLYVGSDLEIGQHRIKIEELRQHLLRWGLTTPDKKYQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLKGTKALTEVVPLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S |
| >CA33412| codons 1-99 PQITLWQRPLVSIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |