Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA624 | CA34423 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 209 |
| 2 | 3TC+D4T | 117 |
| 3 | 3TC+AZT+NFV | 31 |
| 4 | 3TC+D4T+RTV+SQV | 27 |
| 5 | 3TC+D4T+EFV+SQV+Unknown | 34 |
| 6 | 3TC+D4T+EFV+RTV+SQV | 26 |
| 7 | Unknown | 17 |
| 8 | 3TC+ABC+D4T+EFV | 49 |
| 9 | 3TC+ABC+D4T+NVP | 71 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70G, Y115F, Q151M, M184V | A62V, V75I, F77L, F116Y | Y181C, G190GA | V108VI | S68G, T69K, K101KR, T165TI, K166R, D177E, Q207E, R211K, F214FL, H221Y, L228H, K277R, I293V |
| >CA34423| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIKKKDGKGWRKLIDLRELNKRTQDFWEVQLGIPHPAGLRKKKSVTILDVGDAFYSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMIRILEPFRKQNPEIVI CQYVDDLYVASDLEIGQHRTKIEELREHLLKWGLTTPDKKYQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVVPLTEEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, N37NS, L63P |
| >CA33410| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMSLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |