Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8390 | CA34420 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+3TC+SQV | 8 |
| 2 | 3TC+D4T+IDV | 108 |
| 3 | None | 73 |
| 4 | ABC+D4T+EFV | 91 |
| 5 | None | 1 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, Y115F | Y188L | V179D | E6K, V60VI, R83K, K103R, V106VI, K122E, S162C, Q207E, H221HY, V245E, K277R, Q278QH, T286A |
| >CA34420| codons 1-300 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKVVDFRELNKKTQDFWEVQLGIPHPAGLKKRKSITVLDVGDAFFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIDI YQYMDDLLVGSDLEIGQHRTKIEELREHLLRWGFTTPDKKYQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRHLCKLLRGAKALTEVIPLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, L19Q, E35D, A71T |
| >CA33408| codons 1-99 PQITLWQRPIVTIKIGGQQKEALLDTGADDTVLEDMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGHKTIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |