Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5433 | CA34379 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+IDV | 291 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V75T, Q151M, M184V | K219E | I5IV, K11KR, K20KR, A33V, S68G, V111I, I142V, S162Y, E203D, R211RK, F214L, V245E, D250DE, V292I, I293V |
| >CA34379| codons 1-300 PISPVETVPVRLKPGMDGPRVKQWPLTEEKIKVLVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDGTKWRKLTDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDIGDAYFSVPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPMGWKGSPAIFQYSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIDELRQHLLKWGLTTPDEKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEIVPLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | L10F, L24I, K43KT | I15V, R41RK, K55R, I62V, L63P, A71V, I72IT, V77I |
| >CA33364| codons 1-99 PQITLWQRPFVTIKVGGQLKEALIDTGADDTVLEEMNLPGKWTPKLIGGIGGFVRVRQYD QVPIEICGHKVTGTVLIGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |