Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14174 | CA34296 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 9 |
| 2 | 3TC+D4T+NVP | 63 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184V, L210W, T215Y | K219E | Y181C, G190A | V35T, K43N, E44X, V118I, D123E, I135T, S162SN, E203EK, R211K, L228H, A272P, V292I, E297R |
| >CA34296| codons 1-302 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELENXGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPDIVI CQYVDDLYVASDLEIGQHRTKIKELRQHLWKWGFYTPDEKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEIIPLTREAE LE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, L90M | L10I, E35D, M36I, N37D, D60E, L63P, I64V, L89LM, I93IL |
| >CA33280| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFVKVRQYE QIPVEICGHKAIGTVLVGPTPVNIIGRNMMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |