Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA3914 | CA34152 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 111 |
| 2 | AZT+DDC | 39 |
| 3 | 3TC+AZT | 31 |
| 4 | 3TC+D4T | 37 |
| 5 | AZT+DDI+NFV | 77 |
| 6 | 3TC+AZT+EFV+NFV | 91 |
| 7 | APV+D4T+DDI | 31 |
| 8 | ABC+APV+D4T+DDI+LPV | 61 |
| 9 | ABC+DDI+TDF | 28 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33I, T74TP | L10I, R41K, I62IV, L63P, A71T, I72V, V77I, L89LM, I93L |
| >CA34152| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGKWKPKMIGGIGGFIKVRQYD QVPIEICGHKTVGPVLIGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K22R, T39TA, I142V, E169ED, G196E, R211A, F214L, V245M, Q278E, I293V, E297K |
| >CA35167| codons 1-300 PISPIETVPVKLKPGMDGPKVRQWPLTEEKIKALVEICAEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYMDDLYVGSDLEIEQHRTKIEELRQHLLAWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKELCKLLRGTKALTEVVPLTKEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |