Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5718 | CA34151 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | 3TC+AZT+IDV | 35 |
| 3 | D4T+DDI+NFV | 91 |
| 4 | 3TC+ABC+APV+EFV | 18 |
| 5 | 3TC+ABC+APV+NVP | 56 |
| 6 | None | 53 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I47IV, I54IV, V82A, L90M | L33F, K43T | L10I, L19I, K20KR, E35D, M36I, M46X, L63P, I64V, I66IF, A71V, I93IL |
| >CA34151| codons 1-99 PQITLWQRPIVTIKIGGQIREALLDTGADDTIFEDINLPGRWTPKXVGGIGGFVKVRQYD QIPVEFCGHKVIGTVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69S_SS, L74V, M184V, T215Y | A62V, D67E | Y181C, G190S | K101H | K122E, D177E, T200TA, L228H, A272AS, T286A, I293IV |
| >CA35166| codons 1-295 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIKKKESSKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLHKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI CQYVDDLYVSSDLEIGQHRAKIEELRQHLLRWGFYTPDKKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTEVVPL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |