Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14642 | CA34049 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 104 |
| 2 | 3TC+AZT+IDV | 152 |
| 3 | 3TC+AZT+NFV | 17 |
| 4 | ABC+D4T+EFV | 182 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88S | M46MV | L10I, Q18H, E35D, N37S, R41K, L63P, I72V, I93L |
| >CA34049| codons 1-99 PQITLWQRPIVTIKIGGHLKEALLDTGADDTVLEDMSLPGKWKPKVIGGIGGFIKVRQYD QIPIEICGHKAVGTVLVGPTPVNIIGRSLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74LI, M184V | K219Q | K103N | I31IT, K49KR, K64R, K101KQ, K122E, D177E, E203EV, R211K, F214L, D218E, L228H, V245E, I293V, E297A |
| >CA35074| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKTKALVEICTEMEKEGKISRIGPENPYNTPV FAIRKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHPAGLQKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLEIGQHRTKIVELRQHLLKWGLTTPEQKHQKEPPFHWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTAEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |