Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7881 | CA34009 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 55 |
| 2 | 3TC+AZT+DLV+NFV | 16 |
| 3 | ABC+DDI+LPV | 68 |
| 4 | D4T+DDI+LPV+TDF | 16 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54V, V82A, L90M | F53FL, Q58E, L89V | L10I, I13V, L19LV, K20IM, L33L_L, M36I, I62V, L63P, A71V, Q92K |
| >CA34009| codons 1-99 PQITLWQRPIVTVKIGGQVIEALLDTGADDTVLEEINLPGRWKPKIVGGIGGLVKVREYD QVPIEICGHKVIGTVLVGPTPANIIGRNVMTKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, Q151M, T215F | K219E | K103KN, Y181YC | V35T, T69N, K122E, D123DN, I142V, I167IV, I178IM, T200A, Q207K, R211A, R284K, A288AS, I293V, E302D, L303W, A304Q, E305K | N306T |
| >CA35021| codons 1-306 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGVRYQYNVLPMGWKGSPAIFQSSMTKVLEPFRKQNPDMVI CQYMDDLYVGSDLEIGQHRAKIEELRKHLLAWGFFTPDEKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGTKSLTEVVPLTEEAE LDWQKT |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |