Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9935 | CA33902 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 17 |
| 2 | 3TC+AZT | 70 |
| 3 | D4T+DDC+NVP | 26 |
| 4 | 3TC+D4T+NFV | 178 |
| 5 | D4T+DDI+EFV+NFV | 18 |
| 6 | D4T+EFV+NFV+TDF | 26 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | K14R, I15V, K20T, E35D, M36I, N37S, R41K, L63P, K70KR, V75VI |
| >CA33902| codons 1-99 PQITLWQRPLVTIRVGGQLTEALLDTGADNTVLEDISLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGHRAIGTILVGPTPVNIIGRDLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | T215I, K219E | Y181C, G190S | K49R, K101Q, T200A, Q207A, R211K, A272P, V276I, A288T, I293V | K166H |
| >CA34917| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTHILEPFRKQNPDIVI CQYMDDLYVSSDLEIGQHRAKIEELRAHLLKWGFITPDEKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGTKTLTEVVPLTEEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |