Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6361 | CA33836 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 87 |
| 2 | AZT+DDI | 30 |
| 3 | 3TC+AZT+IDV | 205 |
| 4 | 3TC+ABC+AZT+IDV | 43 |
| 5 | ABC+D4T+RTV+SQV | 79 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90LM | V11VI, F53FL, Q58QE, N88T | L10I, I13V, I15V, Q18H, L19I, K20I, M36I, K70R, A71V, I72M |
| >CA33836| codons 1-99 PQITLWQRPIITVKVGGHIIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGLIKVREYD QILIEICGHRVMGTVLVGPTPVNVIGRTLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | E6ED, K20R, T39AE, K104KN, K122E, I135IV, Q207E, E248D, T286A, E297K |
| >CA34843| codons 1-302 PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKNSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLTKEAE LE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |