Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14498 | CA33811 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 22 |
| 2 | 3TC+AZT | 39 |
| 3 | 3TC+AZT+SQV | 9 |
| 4 | 3TC+AZT+IDV | 135 |
| 5 | 3TC+AZT | 109 |
| 6 | None | 86 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10F | K14KR, D60E |
| >CA33811| codons 1-99 PQITLWQRPFVTIRIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYE QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K122KE, K166R, P176S, D177N, G196E, T200A, F214L, V245K, A272P, T286P, I293V, E297R |
| >CA34826| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNSNIVI YQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGPKALTEVVPLTREAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |