Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1289 | CA33796 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 4 |
| 2 | D4T | 17 |
| 3 | 3TC+D4T | 9 |
| 4 | 3TC+D4T+SQV | 48 |
| 5 | 3TC+D4T+NFV | 25 |
| 6 | 3TC+D4T+RTV+SQV | 247 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54L, I84V, L90M | K43T, G73S | L10I, I15V, K20I, N37ND, R57K, I62V, L63P, A71I, P79PS, I93IM |
| >CA33796| codons 1-99 PQITLWQRPIVTIKVGGQLIEALLDTGADDTVLEEMDLPGRWTPKMIGGIGGFLKVKQYD QVPIEICGHKIISTVLVGSTPVNVIGRNLMTQMGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219Q | K20R, V35I, K43Q, T69TN, I135V, I142IV, S162SN, K166KR, D218DE, K277R, I293V |
| >CA34807| codons 1-301 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTEMEQEGKISKIGPENPYNTPV FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQNSMTRILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPEQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVVPLTEEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |