<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
5227 14.ZA.WC405 South Africa 2014 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+ABC+LPV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K22R, V35T, E36A, T39E, K101Q, K122E, D123G, I135K, S162SADY, K173A, Q174K, V179I, T200A, Q207A, R211K, V245Q  
>14.ZA.WC405| codons 1-262
PISPIETVPVKLKPGMDGPKVRQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPDIII
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G16A, L19I, E35D, M36I, N37D, R41K, D60E, H69K, L89M, I93L  
>14.ZA.WC405| codons 1-99
PQITLWQRPLVSIKVAGQIKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYE
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Posada Cespedes, S Learning evolutionary pathways of HIV-1 subtype C under lopinavir treatment IAS 2017, 2017