<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA4828 CA33716 U.S. 2002 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 IDV+ AZT+ 3TC 250

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V L10F K20KM, E35D, M36IV, D60DE, I62IV, L63P, I72T, I85IV, L89LM, I93L  
>CA33716| codons 1-99
PQITLWQRPFVTIKIGGQLMEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFVKVRQYE
QVPIEICGHKATGTVLVGPTPVNIVGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215F     V179D I31L, S68SG, K103R, T200TI, R211K, F214L, V245K, I293V  
>CA34731| codons 1-301
PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIDI
YQYVDDLYVGSDLEIGQHRIKIEELRQHLLKWGLFTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTEEAE
L

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005
Rhee, SY Predictive value of HIV-1 genotypic resistance test interpretation algorithms. J Infect Dis, 2009