Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5051 | CA33669 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NFV | 241 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | Q58QE, N88D | I13IV, K20R, E35D, M36X, N37E, I62IV, L63P, A71AV, I72IT, V77I, I93L |
| >CA33669| codons 1-99 PQITLWQRPLVTVKIGGQLREALLDTGADNTVLEDXELPGRWKPKMIGGIGGFIKVREYD QVPIEICGHKVTGTVLIGPTPVNIIGRDLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V | K219KQ | K20R, T69S, E169D, G196E, Q197QK, R211RK, F214FL, S251T, K277R, I293IV, E297K |
| >CA34684| codons 1-301 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSSRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYVDDLYVGSDLEIEKHRTKIEELRQHLLKWGLTTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDTWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVVPLTKEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |